Module Name Drug Design
Module level, if applicable 4th year
Code, if applicable SFA-990
Semester (s) in which the module is taught Seventh semester
Person responsible for the module apt. Pinus Jumaryatno, M. Phill, Ph.D
Lecturer(s) apt. Pinus Jumaryatno, M. Phill, Ph.D 

Dra. apt. Suparmi, M.Si.
Language English- Indonesia
Relation to curriculum Elective course
Types of teaching and learning Class size Attendance time (hours per week per semester) Forms of active participation Workload
Teaching 50 3 Collaborative discussion Lecture: 3 (hour) x 14 (meeting) 52
Problem Solving  Problem Solving Preparation and follow up 5 (hour) x 14 (self-learning) 70
Total workload 122 hours
ECTS 4.36 ECTS
Credit points 3 CU
Requirements according to examination regulations Minimum attendance at lectures is 75% (according to UII regulation). Final score is evaluated based on assignment and reports (30%), Discipline (10%),  and exam (60%)  
Recommended prerequisites –
Related course Medicinal Chemistry
Module objectives/intended learning By the end of this course students should be able to:

  1. properly explain the basics of rational drug development
  2. describe the physicochemical properties that affect drug action, drug-receptor binding and interactions, the basis of drug-receptor binding
  3. explain the basic principles in QSAR which include physicochemical properties and iso/bioisotsterism
  4. explain the basic principles of prodrug, the purpose of its formation, as well as prodrug design and activation mechanism 
  5. describe the basic principles of structure based design, especially for enzyme as target; rational enzyme inhibitor design
  6. outlines the principles of receptor based design and their applications
  7. apply computer aided drugs design for molecular modeling
  8. properly describe and explain the basic concepts of combinatorial chemistry and their applications
Content The course will cover: 

1. Rational drug development and physicochemical properties influencing drug action

2. Drug-receptor interactions

3. QSAR

4. Prodrug

5. Structure based design

6. Computer aided drug design

7. Combinatorial chemistry
Study and examination requirements and forms of examination Mid-term, Final term, quiz, assignment, and problem solving
Media employed Text books, slides (power points), and video
Reading lists
  1. Kerns, E.H.; Di, L. 2008, Drug-Like Properties: Concepts, Structure Design and Methods: from ADME to Toxicity Optimization, Academic Press, Oxford.
  2. Wolff M. E.,  1995, Burger’s Medicinal Chemistry and Drug Discovery, 5th Edition, Vol. 1. Principles and Practice, edited by, John Wiley & Sons: New York,
  3. Foye, W.O.,  Lemke T.L, and D. A. Williams, 1995, Principles of Medicinal Chemistry, 4th Edition, Williams and Wilkins: Philadelphia.
  4. King F.D., 1994, Medicinal Chemistry: Principles and Practice, Royal Society of Chemistry: Cambridge.